RAB3C

Across TCGA cell cohorts, RAB3C mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAB3C-associated genes across cancer lineages are TBL1Y, CST11, and CLEC4G. Each is linked with RAB3C in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB3C-to-partner and partner-to-RAB3C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBL1Y grouped by RAB3C-low versus RAB3C-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB3C→partner) and Y-score (partner→RAB3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TBL1Y →	+0.730	+4.066	<.001	.002	3	2
BLOOD_Lymphoma	CST11 →	+1.225	+4.714	<.001	.002	3	1
BLOOD_Lymphoma	CLEC4G →	+0.169	+4.714	<.001	.002	3	1
LUNG_SCLC	TPSB2 →	+0.222	+3.381	.001	.007	3	1
BLOOD_Leukemia	SLC52A3 →	+1.366	+3.491	<.001	.008	3	1
BLOOD_Leukemia	SEC14L5 →	+0.633	+3.752	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

TBL1Y by RAB3C expression — BLOOD_Leukemia

Explore this box plot interactively →