RAB3B

Across TCGA cell cohorts, RAB3B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,441 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAB3B-associated GO terms across cancer lineages are Positive regulation of dopamine uptake involved in synaptic transmission, Positive regulation of neurotransmitter uptake, and Establishment of protein localization to membrane. Each is linked with RAB3B in more than 17 cancer types. Because this analysis shows association rather than direction, both RAB3B-to-partner and partner-to-RAB3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of dopamine uptake involved in synaptic transmission grouped by RAB3B-low versus RAB3B-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB3B→partner) and Y-score (partner→RAB3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of dopamine uptake involved in synaptic transmission →	+1.596	+2.839	<.001	<.001	3	18
BLOOD_Myeloma	Positive regulation of neurotransmitter uptake →	-0.343	-1.156	.001	.004	1	17
BONE	Establishment of protein localization to membrane →	+0.047	+1.287	.003	.004	3	12
OESOPHAGUS	Regulation of dopamine uptake involved in synaptic transmission →	-0.392	-1.241	.001	.009	3	12
BONE	Positive regulation of supramolecular fiber organization →	+0.093	+1.951	<.001	<.001	3	11
SKIN	Positive regulation of cell-substrate adhesion →	+0.097	+1.212	<.001	.004	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,441 associations by consensus.

Positive regulation of dopamine uptake involved in synaptic transmission by RAB3B expression — LUNG_NSCLC_LUSC

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