RAB3A

Across TCGA patient cohorts, RAB3A mutation is significantly associated with the immune_cell of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB3A-associated genes across cancer lineages are CD8+ Tcm, MPP, and CMP. Each is linked with RAB3A in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB3A-to-partner and partner-to-RAB3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ Tcm grouped by RAB3A-low versus RAB3A-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB3A→partner) and Y-score (partner→RAB3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CD8+ Tcm →	+0.151	+5.917	<.001	.032	3	2
BLCA	MPP →	+0.033	+3.194	.011	.048	3	2
UCEC	CMP →	+0.027	+1.595	.038	.045	3	2
KIRP	Fibroblasts →	+0.063	+5.301	<.001	.048	3	1
COAD	CD8+ T-cells →	+0.089	+6.142	<.001	.027	3	1
COAD	CD4+ naive T-cells →	+0.047	+6.142	<.001	.027	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

CD8+ Tcm by RAB3A expression — COAD

Explore this box plot interactively →