RAB39A

Across TCGA patient cohorts, RAB39A mutation is significantly associated with the RNA expression of many other genes, with 1,937 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB39A-associated genes across cancer lineages are OR10H4, LINC00434, and OR2T3. Each is linked with RAB39A in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB39A-to-partner and partner-to-RAB39A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10H4 grouped by RAB39A-low versus RAB39A-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB39A→partner) and Y-score (partner→RAB39A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	OR10H4 →	+0.112	+6.342	<.001	.001	3	2
CESC	LINC00434 →	+0.244	+5.103	<.001	.008	3	2
LUSC	OR2T3 →	+0.045	+4.792	.004	.006	3	2
COAD	OR51V1 →	+0.103	+7.741	<.001	.009	3	2
CESC	KRTAP1-4 →	+0.131	+7.164	<.001	<.001	3	1
CESC	RNU6-1067P →	+0.852	+6.569	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,937 associations by consensus.

OR10H4 by RAB39A expression — CESC

Explore this box plot interactively →