RAB39A

Across TCGA cell cohorts, RAB39A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,249 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RAB39A-associated GO terms across cancer lineages are Regulation of DNA repair, Transcription initiation at RNA polymerase I promoter, and Regulation of double-strand break repair via homologous recombination. Each is linked with RAB39A in more than 11 cancer types. Because this analysis shows association rather than direction, both RAB39A-to-partner and partner-to-RAB39A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA repair grouped by RAB39A-low versus RAB39A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB39A→partner) and Y-score (partner→RAB39A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of DNA repair →	+0.088	+1.675	.001	<.001	3	12
BONE	Transcription initiation at RNA polymerase I promoter →	+0.092	+0.982	<.001	.002	3	10
BONE	Regulation of double-strand break repair via homologous recombination →	+0.110	+1.405	<.001	<.001	3	10
BONE	Protein-RNA complex organization →	+0.079	+1.195	<.001	<.001	3	10
BONE	Phagosome acidification →	-0.209	-1.057	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Epigenetic regulation of gene expression →	+0.054	+1.284	<.001	.002	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,249 associations by consensus.

Regulation of DNA repair by RAB39A expression — BONE

Explore this box plot interactively →