RAB39A

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RAB39A mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAB39A-associated genes across cancer lineages are IQCF6 and CD300H. Each is linked with RAB39A in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB39A-to-partner and partner-to-RAB39A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IQCF6 grouped by RAB39A-low versus RAB39A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB39A→partner) and Y-score (partner→RAB39A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEIQCF6 →+0.311+4.467<.001.00431
LARGE_INTESTINECD300H →+0.033+4.415<.001.00731
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

IQCF6 by RAB39A expression — LARGE_INTESTINE

Box plot of IQCF6 in RAB39A-low vs RAB39A-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration