RAB37

Across TCGA pan-cancer cohorts, RAB37 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated RAB37 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RAB37 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated RAB37 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

HNSC, PDAC, and LUAD are the cancer types where RAB37 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.384	0.879	<.001	43	view →
PDAC	DFS	Quartile	II,III,IV	0.392	0.647	.002	16	view →
LUAD	OS	Tertile	II,III,IV	0.357	1.000	.013	10	view →
LSCC	DFS	Median	III,IV	0.925	0.621	.022	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RAB37–HNSC (DFS)

Open the HNSC breakdown →