RAB37

Across TCGA pan-cancer cohorts, RAB37 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of RAB37’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RAB37 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RAB37 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

KIRC, LUAD, and LUSC are the cancer types where RAB37 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RAB37 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+1.782	<.001	12	view →
LUAD	All	III,IV	−1.142	<.001	10	view →
LUSC	Male	III,IV	−2.460	<.001	8	view →
COAD	Female	III,IV	−1.590	<.001	8	view →
BLCA	Male	All	−1.396	<.001	7	view →
KICH	Male	II,III,IV	−0.992	<.001	7	view →
UCEC	All	All	−0.829	<.001	6	view →
CHOL	Male	All	−1.233	.001	4	view →
READ	All	All	−1.033	.009	4	view →
HNSC	All	All	−0.297	.017	4	view →
KIRP	All	All	+0.639	.001	3	view →
PRAD	All	All	−0.548	.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

RAB37–KIRC

Open the KIRC breakdown →