RAB37

Across TCGA cell cohorts, RAB37 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAB37-associated genes across cancer lineages are IFNG, SERPINA12, and TMEM114. Each is linked with RAB37 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB37-to-partner and partner-to-RAB37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNG grouped by RAB37-low versus RAB37-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB37→partner) and Y-score (partner→RAB37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	IFNG →	+0.220	+4.152	<.001	.009	3	1
BLOOD_Leukemia	SERPINA12 →	+0.059	+5.060	<.001	.001	3	1
BLOOD_Leukemia	TMEM114 →	+0.022	+4.539	.004	.007	3	1
BLOOD_Leukemia	SLC5A8 →	+0.139	+5.786	<.001	<.001	3	1
BLOOD_Leukemia	CFHR2 →	+0.296	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

IFNG by RAB37 expression — BLOOD_Leukemia

Explore this box plot interactively →