RAB36

Across TCGA pan-cancer cohorts, RAB36 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RAB36 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RAB36 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated RAB36 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

CCRCC, LUAD, and PDAC are the cancer types where RAB36 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	II,III,IV	0.198	0.830	.024	18	view →
LUAD	DFS	Median	III,IV	0.580	0.892	.026	10	view →
PDAC	DFS	Median	II,III,IV	0.318	0.628	.011	7	view →
UCEC	DFS	Median	All	0.965	0.858	.027	2	view →
LSCC	OS	Median	All	0.824	1.000	.036	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RAB36–CCRCC (DFS)

Open the CCRCC breakdown →