RAB33B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RAB33B mutation is significantly associated with the RNA expression of many other genes, with 1,289 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB33B-associated genes across cancer lineages are LINC02252, DPPA5P1, and KRTAP23-1. Each is linked with RAB33B in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB33B-to-partner and partner-to-RAB33B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02252 grouped by RAB33B-low versus RAB33B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB33B→partner) and Y-score (partner→RAB33B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMLINC02252 →+0.176+4.661<.001.00432
BLCADPPA5P1 →+0.147+4.719.006.00332
UCECKRTAP23-1 →+0.244+2.717.001.00632
UCECRNU6-1213P →+0.293+4.292<.001<.00132
BLCAUBTFL11 →+0.043+4.363<.001.00732
UCECCELF1 →+0.485+3.191.007.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,289 associations by consensus.

LINC02252 by RAB33B expression — SKCM

Box plot of LINC02252 in RAB33B-low vs RAB33B-high samples in SKCM.

Explore this box plot interactively →

Exploration