RAB32

Across TCGA patient cohorts, RAB32 mutation is significantly associated with the RNA expression of many other genes, with 295 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB32-associated genes across cancer lineages are RNU2-50P, LYPLA1P1, and FRG1HP. Each is linked with RAB32 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB32-to-partner and partner-to-RAB32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU2-50P grouped by RAB32-low versus RAB32-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB32→partner) and Y-score (partner→RAB32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU2-50P →	+0.352	+2.575	.006	.006	3	2
UCEC	LYPLA1P1 →	+0.069	+3.879	<.001	.009	3	2
UCEC	FRG1HP →	+0.671	+3.354	.002	.005	3	1
UCEC	MIR6856 →	+0.524	+2.792	<.001	.006	3	1
COAD	MBD3L3 →	+0.129	+7.741	<.001	.009	3	1
UCEC	AAGAB →	+0.645	+3.364	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 295 associations by consensus.

RNU2-50P by RAB32 expression — UCEC

Explore this box plot interactively →