RAB32

Across TCGA pan-cancer cohorts, RAB32 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of RAB32’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RAB32 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RAB32 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

HNSC, KIRC, and KIRP are the cancer types where RAB32 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RAB32 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	+2.040	<.001	12	view →
KIRC	Female	All	+1.144	<.001	12	view →
KIRP	All	III,IV	+1.181	<.001	11	view →
LUAD	All	All	−0.474	<.001	8	view →
LUSC	All	All	−0.461	<.001	8	view →
COAD	All	All	−0.476	.009	6	view →
THCA	Male	All	+0.610	.002	5	view →
BLCA	Male	All	−1.195	<.001	4	view →
BRCA	Female	All	−0.308	<.001	4	view →
CHOL	All	All	+1.428	.001	2	view →
UCEC	All	All	−0.943	.004	2	view →
KICH	Female	All	−0.646	.004	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

RAB32–HNSC

Open the HNSC breakdown →