RAB32

Across TCGA cell cohorts, RAB32 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,803 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RAB32-associated GO terms across cancer lineages are Negative regulation of Rho protein signal transduction, Positive regulation of cell-substrate junction organization, and Regulation of plasminogen activation. Each is linked with RAB32 in more than 10 cancer types. Because this analysis shows association rather than direction, both RAB32-to-partner and partner-to-RAB32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of Rho protein signal transduction grouped by RAB32-low versus RAB32-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB32→partner) and Y-score (partner→RAB32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of Rho protein signal transduction →	+0.171	+3.435	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Positive regulation of cell-substrate junction organization →	+0.162	+1.273	<.001	.005	2	11
BONE	Regulation of plasminogen activation →	+0.261	+3.635	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Peptidyl-lysine oxidation →	+1.581	+2.031	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Positive regulation of protein exit from endoplasmic reticulum →	+0.127	+2.525	.002	.009	3	10
SOFT_TISSUE	Intestinal lipid absorption →	+0.262	+1.864	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,803 associations by consensus.

Negative regulation of Rho protein signal transduction by RAB32 expression — BONE

Explore this box plot interactively →