RAB31

Across TCGA pan-cancer cohorts, RAB31 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated RAB31 data layer compared with 3 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in uveal melanoma (UVM), where higher RAB31 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RAB31 expression acts as an unfavorable survival marker, although some lineages such as SKCM and UCEC show a favorable association.

UVM, STAD, and BLCA are the cancer types where RAB31 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.397	0.785	<.001	141	view →
STAD	OS	Quartile	All	0.470	0.657	.007	69	view →
BLCA	DFS	Median	All	0.392	0.581	.009	30	view →
SKCM	DFS	Quartile	All	0.326	0.156	.001	29	view →
LAML	DFS	Tertile	All	0.486	0.720	.008	26	view →
GBM	DFS	Median	All	0.208	0.308	.008	12	view →
UCEC	DFS	Tertile	II,III,IV	0.876	0.736	.008	12	view →
ESCA	DFS	Median	III,IV	0.547	0.305	.006	12	view →
HNSC	OS	Median	All	0.711	0.790	.015	10	view →
PAAD	OS	Quartile	II,III,IV	0.711	0.458	.015	7	view →
BRCA	OS	Tertile	IV	0.746	0.262	.012	6	view →
KIRC	DFS	Median	All	0.845	0.742	.025	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

RAB31–UVM (DFS)

Open the UVM breakdown →