RAB30-DT

Across TCGA pan-cancer cohorts, RAB30-DT RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated RAB30-DT data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RAB30-DT RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RAB30-DT expression acts as an unfavorable survival marker, although some lineages such as LUSC and KIRC show a favorable association.

ACC, KICH, and LUSC are the cancer types where RAB30-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.194	0.649	<.001	82	view →
KICH	OS	Median	III,IV	0.340	1.000	.001	57	view →
LUSC	OS	Median	All	0.828	0.724	.001	44	view →
LIHC	OS	Median	All	0.687	0.870	<.001	43	view →
KIRC	OS	Tertile	All	0.860	0.770	.004	37	view →
LUAD	DFS	Median	All	0.831	0.698	.005	28	view →
ESCA	DFS	Tertile	III,IV	0.289	0.511	.013	27	view →
BRCA	DFS	Median	IV	0.789	0.301	<.001	24	view →
DLBC	DFS	Tertile	All	1.000	0.654	.003	23	view →
PRAD	DFS	Tertile	All	0.693	0.883	.005	18	view →
READ	DFS	Median	II,III,IV	0.633	0.371	.003	17	view →
STAD	DFS	Median	IV	0.310	0.677	.031	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

RAB30-DT–ACC (DFS)

Open the ACC breakdown →