RAB30-DT

Across TCGA pan-cancer cohorts, RAB30-DT RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of RAB30-DT’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RAB30-DT RNA is repressed in tumor relative to normal tissue. In most cancer types RAB30-DT is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and LIHC are the cancer types where RAB30-DT tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RAB30-DT RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	III,IV	−1.140	<.001	10	view →
THCA	Male	All	−0.646	<.001	10	view →
LIHC	Male	All	+1.048	<.001	9	view →
HNSC	Male	All	+0.597	<.001	8	view →
LUSC	All	All	+0.474	<.001	6	view →
CHOL	Female	All	+1.253	<.001	5	view →
STAD	All	II,III,IV	+0.606	.002	4	view →
LUAD	All	All	+0.453	<.001	4	view →
KIRP	All	All	−0.392	.006	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

RAB30-DT–KICH

Open the KICH breakdown →