RAB2A

Across TCGA pan-cancer cohorts, RAB2A mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RAB2A data layer compared with 25 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher RAB2A mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RAB2A expression acts as an unfavorable survival marker, although some lineages such as COAD and GBM show a favorable association.

COAD, CCRCC, and PDAC are the cancer types where RAB2A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	1.000	0.901	.025	30	view →
CCRCC	OS	Tertile	All	0.727	0.944	.002	18	view →
PDAC	OS	Median	IV	0.381	0.951	.006	9	view →
GBM	DFS	Tertile	All	0.888	0.683	.020	7	view →
LUAD	DFS	Median	III,IV	0.315	0.948	.008	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RAB2A–COAD (DFS)

Open the COAD breakdown →