RAB27A

Across TCGA cell cohorts, RAB27A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,902 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RAB27A-associated GO terms across cancer lineages are Cytoplasmic pattern recognition receptor signaling pathway, Viral protein processing, and Intracellular receptor signaling pathway. Each is linked with RAB27A in more than 10 cancer types. Because this analysis shows association rather than direction, both RAB27A-to-partner and partner-to-RAB27A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic pattern recognition receptor signaling pathway grouped by RAB27A-low versus RAB27A-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB27A→partner) and Y-score (partner→RAB27A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Cytoplasmic pattern recognition receptor signaling pathway →	+0.085	+1.257	<.001	.001	3	11
LIVER	Viral protein processing →	+0.146	+1.529	<.001	<.001	3	10
LIVER	Intracellular receptor signaling pathway →	+0.058	+1.587	.007	.007	2	11
CNS	Regulation of response to cytokine stimulus →	+0.065	+1.677	<.001	<.001	3	10
BLOOD_Lymphoma	Urokinase plasminogen activator signaling pathway →	+0.650	+1.627	<.001	<.001	3	10
BONE	Positive regulation of protein exit from endoplasmic reticulum →	+0.169	+2.269	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,902 associations by consensus.

Cytoplasmic pattern recognition receptor signaling pathway by RAB27A expression — SOFT_TISSUE

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