RAB21

Across TCGA patient cohorts, RAB21 mutation is significantly associated with the RNA expression of many other genes, with 434 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB21-associated genes across cancer lineages are MLLT10P2, AQP7P4, and RNU6-351P. Each is linked with RAB21 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB21-to-partner and partner-to-RAB21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MLLT10P2 grouped by RAB21-low versus RAB21-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB21→partner) and Y-score (partner→RAB21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MLLT10P2 →	+0.313	+3.434	<.001	.001	3	2
UCEC	AQP7P4 →	+0.077	+4.220	<.001	<.001	3	2
COAD	RNU6-351P →	+0.284	+7.741	<.001	.009	3	2
BRCA	MIR6853 →	+0.364	+9.057	<.001	.003	3	1
UCEC	LINC01943 →	+0.863	+3.354	<.001	.005	3	1
KIRP	MTATP6P31 →	+0.168	+5.159	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 434 associations by consensus.

MLLT10P2 by RAB21 expression — UCEC

Explore this box plot interactively →