RAB1B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RAB1B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,886 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAB1B-associated GO terms across cancer lineages are Positive regulation of attachment of mitotic spindle microtubules to kinetochore, Regulation of metaphase plate congression, and Positive regulation of attachment of spindle microtubules to kinetochore. Each is linked with RAB1B in more than 13 cancer types. Because this analysis shows association rather than direction, both RAB1B-to-partner and partner-to-RAB1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of attachment of mitotic spindle microtubules to kinetochore grouped by RAB1B-low versus RAB1B-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB1B→partner) and Y-score (partner→RAB1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTPositive regulation of attachment of mitotic spindle microtubules to kinetochore →+0.188+1.069.001.003214
URINARY_TRACTRegulation of metaphase plate congression →+0.162+0.975<.001<.001313
URINARY_TRACTPositive regulation of attachment of spindle microtubules to kinetochore →+0.149+1.075.001.001312
BLOOD_LymphomaRegulation of anaphase-promoting complex-dependent catabolic process →+0.107+0.606<.001<.001312
OVARYRegulation of Golgi inheritance →+0.171+0.825<.001<.001312
URINARY_TRACTPositive regulation of anaphase-promoting complex-dependent catabolic process →+0.119+0.935<.001<.001312
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,886 associations by consensus.

Positive regulation of attachment of mitotic spindle microtubules to kinetochore by RAB1B expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Positive regulation of attachment of mitotic spindle microtubules to kinetochore in RAB1B-low vs RAB1B-high samples in UPPER_AERODIGESTIVE_TRACT.

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Exploration