RAB1B

Across TCGA pan-cancer cohorts, RAB1B RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated RAB1B data layer compared with 4 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in small cell lung cancer (SCLC), where higher RAB1B RNA is associated with better overall survival. In most high-consensus cancer types, elevated RAB1B expression acts as an unfavorable survival marker, although some lineages such as SCLC and KIRC show a favorable association.

SCLC, ACC, and LIHC are the cancer types where RAB1B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	OS	Median	All	0.845	0.563	<.001	77	view →
ACC	DFS	Tertile	All	0.163	0.745	<.001	49	view →
LIHC	DFS	Median	All	0.287	0.539	.001	45	view →
KICH	DFS	Median	III,IV	0.428	1.000	.004	43	view →
PAAD	OS	Tertile	All	0.456	0.795	<.001	42	view →
KIRC	DFS	Tertile	All	0.741	0.510	<.001	38	view →
LUAD	OS	Median	All	0.262	0.505	<.001	36	view →
LGG	OS	Median	All	0.754	0.868	<.001	31	view →
MESO	DFS	Median	IV	0.195	0.430	.015	31	view →
STAD	DFS	Median	III,IV	0.577	0.392	.012	27	view →
LAML	DFS	Tertile	All	0.329	0.528	.007	26	view →
LUSC	DFS	Median	All	0.690	0.798	.001	26	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

RAB1B–SCLC (OS)

Open the SCLC breakdown →