RAB1A

Across TCGA pan-cancer cohorts, RAB1A mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated RAB1A data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RAB1A mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated RAB1A expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

CCRCC, HNSC, and GBM are the cancer types where RAB1A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	III,IV	0.392	0.843	.009	15	view →
HNSC	DFS	Tertile	All	0.854	0.689	.011	12	view →
GBM	OS	Quartile	All	0.292	0.557	.023	2	view →
LSCC	OS	Median	All	0.703	0.896	.011	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RAB1A–CCRCC (DFS)

Open the CCRCC breakdown →