RAB1A

Across TCGA patient cohorts, RAB1A mutation is significantly associated with the RNA expression of many other genes, with 818 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB1A-associated genes across cancer lineages are RNU4-72P, HSPE1-MOB4, and LINC01607. Each is linked with RAB1A in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB1A-to-partner and partner-to-RAB1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-72P grouped by RAB1A-low versus RAB1A-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB1A→partner) and Y-score (partner→RAB1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU4-72P →	+0.511	+4.646	.001	.004	3	2
UCEC	HSPE1-MOB4 →	+0.198	+2.799	<.001	.001	3	1
UCEC	LINC01607 →	-0.775	-3.574	.001	.003	3	1
UCEC	UBE2Q2P6 →	+0.164	+2.328	.001	.004	3	1
UCEC	UHRF1 →	+1.273	+3.595	<.001	.001	3	1
UCEC	RNA5SP411 →	+1.124	+2.616	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 818 associations by consensus.

RNU4-72P by RAB1A expression — COAD

Explore this box plot interactively →