RAB14

Across TCGA pan-cancer cohorts, RAB14 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RAB14 data layer compared with 19 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RAB14 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RAB14 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

CCRCC, PDAC, and HNSC are the cancer types where RAB14 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	II,III,IV	1.000	0.778	.008	11	view →
PDAC	DFS	Median	All	0.692	0.827	.005	10	view →
HNSC	DFS	Median	II,III,IV	0.992	0.907	.016	7	view →
UCEC	DFS	Median	II,III,IV	0.883	0.532	.020	4	view →
LUAD	OS	Quartile	III,IV	0.680	0.188	.021	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RAB14–CCRCC (DFS)

Open the CCRCC breakdown →