RAB11FIP5

Across TCGA patient cohorts, RAB11FIP5 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB11FIP5-associated genes across cancer lineages are JNK2, Caspase-7-cleavedD198, and Caspase-8. Each is linked with RAB11FIP5 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB11FIP5-to-partner and partner-to-RAB11FIP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK2 grouped by RAB11FIP5-low versus RAB11FIP5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB11FIP5→partner) and Y-score (partner→RAB11FIP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.229	+1.807	<.001	.004	3	2
UCEC	Caspase-7-cleavedD198 →	+0.725	+3.807	<.001	<.001	3	2
UCEC	Caspase-8 →	-0.239	-3.221	.005	<.001	3	2
UCEC	C-Raf →	+0.125	+1.765	.010	.013	3	2
UCEC	14-3-3_beta →	-0.108	-3.673	.001	.001	3	1
UCEC	eEF2 →	+0.259	+1.247	.033	.045	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

JNK2 by RAB11FIP5 expression — UCEC

Explore this box plot interactively →