RAB11FIP5

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RAB11FIP5 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated RAB11FIP5 data layer compared with 3 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher RAB11FIP5 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RAB11FIP5 expression acts as an unfavorable survival marker, although some lineages such as KIRC and CHOL show a favorable association.

MESO, ACC, and KIRC are the cancer types where RAB11FIP5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
MESOOSMedianAll0.2720.495<.001108view →
ACCDFSMedianAll0.2360.638<.00189view →
KIRCOSMedianAll0.7460.519<.00185view →
LIHCDFSQuartileAll0.3890.631<.00178view →
BLCADFSTertileAll0.2910.484<.00156view →
OVOSTertileAll0.2510.363.00542view →
UCECDFSQuartileAll0.6840.857.00538view →
CESCDFSQuartileAll0.6670.875.00134view →
PAADDFSQuartileAll0.2040.465.00627view →
LGGOSMedianAll0.7610.897.00223view →
LUADDFSQuartileAll0.2670.439.00820view →
KICHOSMedianIII,IV0.4670.863.01113view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

RAB11FIP5–MESO (OS)

Kaplan–Meier survival curve for RAB11FIP5 RNA-high vs -low samples in MESO.

Open the MESO breakdown →

Exploration