RAB11FIP4

Across TCGA patient cohorts, RAB11FIP4 mutation is significantly associated with the total protein of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB11FIP4-associated genes across cancer lineages are MSH6, PCNA, and ERK2. Each is linked with RAB11FIP4 in more than 2 cancer types. Because this analysis shows association rather than direction, both RAB11FIP4-to-partner and partner-to-RAB11FIP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MSH6 grouped by RAB11FIP4-low versus RAB11FIP4-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB11FIP4→partner) and Y-score (partner→RAB11FIP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MSH6 →	-0.496	-2.974	.014	.036	3	2
COAD	PCNA →	+0.369	+2.820	.004	.035	3	2
UCEC	ERK2 →	+0.137	+2.584	.033	.010	3	2
UCEC	MSH2 →	-0.224	-1.973	.003	.029	3	2
UCEC	mTOR_pS2448 →	-0.126	-1.482	.011	.027	3	2
UCEC	ATM →	-0.490	-1.584	.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

MSH6 by RAB11FIP4 expression — COAD

Explore this box plot interactively →