RAB11FIP4

Across TCGA cell cohorts, RAB11FIP4 mutation is significantly associated with the RNA expression of many other genes, with 76 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAB11FIP4-associated genes across cancer lineages are NDUFAF4, PLA2G12A, and PRDM7. Each is linked with RAB11FIP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB11FIP4-to-partner and partner-to-RAB11FIP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NDUFAF4 grouped by RAB11FIP4-low versus RAB11FIP4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB11FIP4→partner) and Y-score (partner→RAB11FIP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	NDUFAF4 →	+0.697	+3.212	.001	.006	3	1
LARGE_INTESTINE	PLA2G12A →	+0.780	+3.212	.004	.006	3	1
LARGE_INTESTINE	PRDM7 →	+0.208	+3.472	<.001	.003	3	1
LARGE_INTESTINE	RPUSD3 →	+0.482	+3.212	.003	.006	3	1
LARGE_INTESTINE	POLR1C →	+0.444	+3.212	.006	.006	3	1
LARGE_INTESTINE	OR4F4 →	+0.014	+2.688	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 76 associations by consensus.

NDUFAF4 by RAB11FIP4 expression — LARGE_INTESTINE

Explore this box plot interactively →