RAB11FIP3

Across TCGA patient cohorts, RAB11FIP3 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB11FIP3-associated genes across cancer lineages are Annexin-1, EGFR_pY1068, and A-Raf_pS299. Each is linked with RAB11FIP3 in more than 2 cancer types. Because this analysis shows association rather than direction, both RAB11FIP3-to-partner and partner-to-RAB11FIP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Annexin-1 grouped by RAB11FIP3-low versus RAB11FIP3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB11FIP3→partner) and Y-score (partner→RAB11FIP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin-1 →	+0.569	+3.019	.020	.019	3	3
UCEC	EGFR_pY1068 →	-0.290	-2.584	.013	.011	3	1
UCEC	A-Raf_pS299 →	-0.110	-3.000	.047	.036	3	1
UCEC	ERK2 →	+0.284	+3.459	.001	.005	3	1
UCEC	MAPK_pT202_Y204 →	-0.637	-3.156	.003	.018	3	1
UCEC	Rab25 →	-0.490	-3.000	.001	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Annexin-1 by RAB11FIP3 expression — UCEC

Explore this box plot interactively →