RAB11FIP3

Across TCGA pan-cancer cohorts, RAB11FIP3 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated RAB11FIP3 data layer compared with 5 for mutation status and 7 for mass-spec protein.

The strongest signal is observed in uveal melanoma (UVM), where higher RAB11FIP3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RAB11FIP3 expression acts as an unfavorable survival marker, although some lineages such as PAAD and KIRC show a favorable association.

UVM, PAAD, and KIRC are the cancer types where RAB11FIP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.326	0.684	<.001	115	view →
PAAD	OS	Tertile	All	0.563	0.292	.001	50	view →
KIRC	DFS	Tertile	All	0.756	0.470	.004	39	view →
LIHC	DFS	Quartile	All	0.401	0.580	.002	28	view →
BRCA	OS	Median	III,IV	0.949	0.858	.002	26	view →
HNSC	DFS	Tertile	IV	0.493	0.222	.001	25	view →
LGG	DFS	Tertile	All	0.672	0.800	.004	18	view →
PRAD	DFS	Median	All	0.834	0.936	<.001	18	view →
READ	OS	Median	All	0.931	0.324	.009	17	view →
ACC	OS	Median	All	0.757	0.967	.021	15	view →
LUSC	DFS	Tertile	III,IV	0.537	1.000	.028	13	view →
ESCA	OS	Median	IV	0.222	0.698	.006	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

RAB11FIP3–UVM (DFS)

Open the UVM breakdown →