RAB11FIP3

Across TCGA cell cohorts, RAB11FIP3 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible RAB11FIP3-associated genes across cancer lineages are CST9L, KRT37, and SLC17A1. Each is linked with RAB11FIP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB11FIP3-to-partner and partner-to-RAB11FIP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CST9L grouped by RAB11FIP3-low versus RAB11FIP3-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB11FIP3→partner) and Y-score (partner→RAB11FIP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	CST9L →	+0.045	+4.643	<.001	.004	3	1
LUNG_SCLC	KRT37 →	+0.081	+4.044	.001	.009	3	1
LUNG_SCLC	SLC17A1 →	+0.028	+4.269	.001	.005	3	1
LUNG_SCLC	DEFA6 →	+0.593	+4.044	.001	.009	3	1
LUNG_SCLC	KRTAP4-3 →	+0.027	+4.643	<.001	.004	3	1
LUNG_SCLC	KRTAP9-3 →	+0.042	+4.643	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

CST9L by RAB11FIP3 expression — LUNG_SCLC

Explore this box plot interactively →