RAB11B-AS1

Across TCGA pan-cancer cohorts, RAB11B-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of RAB11B-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where RAB11B-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types RAB11B-AS1 is over-expressed in tumor, although a few such as LUAD and BRCA show the opposite, repressed pattern.

LUAD, KIRC, and BRCA are the cancer types where RAB11B-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RAB11B-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	II,III,IV	−0.678	<.001	9	view →
KIRC	All	IV	+0.459	<.001	9	view →
BRCA	All	II,III,IV	−0.743	<.001	6	view →
HNSC	Male	II,III,IV	−0.499	<.001	5	view →
STAD	Male	All	−0.415	<.001	5	view →
UCEC	All	IV	−1.320	.028	2	view →
CHOL	Male	All	−1.125	.008	2	view →
ESCA	All	All	−0.448	.014	2	view →
PRAD	All	All	+0.227	.011	2	view →
LUSC	Male	III,IV	−0.949	.037	1	view →
COAD	Male	IV	+0.409	.046	1	view →
COAD	Female	III,IV	−0.347	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

RAB11B-AS1–LUAD

Open the LUAD breakdown →