RAB11A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RAB11A mutation is significantly associated with the RNA expression of many other genes, with 2,653 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB11A-associated genes across cancer lineages are RNU1-33P, TEMN3-AS1, and LIN7C. Each is linked with RAB11A in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB11A-to-partner and partner-to-RAB11A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-33P grouped by RAB11A-low versus RAB11A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB11A→partner) and Y-score (partner→RAB11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU1-33P →+0.147+2.607.003.00532
UCECTEMN3-AS1 →+0.180+2.464<.001.00732
UCECLIN7C →+0.574+2.850.001.00131
UCECIMMP1L →+0.511+3.839<.001<.00131
UCECAPIP →+0.473+3.595.004.00131
UCECEIF3M →+0.457+2.764.004.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,653 associations by consensus.

RNU1-33P by RAB11A expression — UCEC

Box plot of RNU1-33P in RAB11A-low vs RAB11A-high samples in UCEC.

Explore this box plot interactively →

Exploration