RAB11A

Across TCGA patient cohorts, RAB11A mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB11A-associated genes across cancer lineages are ATM, ACC1, and INPP4B. Each is linked with RAB11A in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB11A-to-partner and partner-to-RAB11A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by RAB11A-low versus RAB11A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB11A→partner) and Y-score (partner→RAB11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.500	-2.986	.009	.035	3	2
UCEC	ACC1 →	+0.340	+1.700	.027	.044	3	1
UCEC	INPP4B →	-0.349	-2.321	.010	.034	2	2
UCEC	Ku80 →	+0.376	+2.920	<.001	.001	3	1
UCEC	MEK1 →	+0.350	+2.115	.024	.017	3	1
UCEC	Notch1 →	+0.147	+1.700	.014	.044	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

ATM by RAB11A expression — UCEC

Explore this box plot interactively →