RAB11A

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RAB11A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,584 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAB11A-associated GO terms across cancer lineages are Golgi lumen acidification, Regulation of translation at postsynapse, modulating synaptic transmission, and Protein localization to nucleolus. Each is linked with RAB11A in more than 9 cancer types. Because this analysis shows association rather than direction, both RAB11A-to-partner and partner-to-RAB11A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi lumen acidification grouped by RAB11A-low versus RAB11A-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB11A→partner) and Y-score (partner→RAB11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaGolgi lumen acidification →+0.107+0.590<.001<.001310
SOFT_TISSUERegulation of translation at postsynapse, modulating synaptic transmission →+0.098+0.644<.001.003310
PANCREASProtein localization to nucleolus →-0.123-0.715<.001<.00139
BLOOD_LeukemiaRegulation of translation at postsynapse →+0.102+0.582<.001<.00138
LUNG_NSCLC_LUADNegative regulation of glial cell migration →+0.175+0.679<.001<.00138
SKINMedium-chain fatty acid catabolic process →+0.114+0.338.006.00238
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,584 associations by consensus.

Golgi lumen acidification by RAB11A expression — BLOOD_Myeloma

Box plot of Golgi lumen acidification in RAB11A-low vs RAB11A-high samples in BLOOD_Myeloma.

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Exploration