RAB11A

Across TCGA cell cohorts, RAB11A mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. CNS shows the largest number of these associations.

The most reproducible RAB11A-associated genes across cancer lineages are DEFB115, KLRF2, and TECRL. Each is linked with RAB11A in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB11A-to-partner and partner-to-RAB11A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFB115 grouped by RAB11A-low versus RAB11A-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB11A→partner) and Y-score (partner→RAB11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	DEFB115 →	+0.263	+6.357	<.001	<.001	3	1
CNS	KLRF2 →	+0.059	+5.754	<.001	.002	3	1
LARGE_INTESTINE	TECRL →	+0.026	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

DEFB115 by RAB11A expression — CNS

Explore this box plot interactively →