R3HDM2

Across TCGA patient cohorts, R3HDM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,134 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible R3HDM2-associated proteins across cancer lineages are SART3, ADNP, and KHDRBS1_S58. Each is linked with R3HDM2 in more than 4 cancer types. Because this analysis shows association rather than direction, both R3HDM2-to-partner and partner-to-R3HDM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, R3HDM2 versus SART3 in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (R3HDM2→partner) and Y-score (partner→R3HDM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SART3 →	+0.295	+0.550	<.001	<.001	3	5
LSCC	ADNP →	+0.328	+0.445	<.001	<.001	3	5
PDAC	KHDRBS1_S58 →	+0.317	+0.238	.001	.001	3	5
GBM	VEZF1 →	+0.434	+0.493	<.001	<.001	3	5
LSCC	SSB →	+0.213	+0.342	<.001	<.001	3	5
LSCC	GBF1_S662 →	-0.350	-0.533	.005	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,134 associations by consensus.

R3HDM2 vs SART3 — LSCC

Explore this scatter interactively →