R3HCC1

Across TCGA pan-cancer cohorts, R3HCC1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated R3HCC1 data layer compared with 25 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher R3HCC1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated R3HCC1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and GBM show a favorable association.

CCRCC, LSCC, and OV are the cancer types where R3HCC1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	III,IV	0.724	0.353	.007	16	view →
LSCC	DFS	Median	All	0.384	0.875	.005	10	view →
OV	DFS	Tertile	All	0.800	1.000	.046	4	view →
GBM	DFS	Median	All	0.439	0.288	.018	4	view →
UCEC	OS	Quartile	III,IV	0.890	0.424	.040	4	view →
PDAC	DFS	Quartile	III,IV	0.168	0.904	.013	4	view →
LUAD	OS	Median	II,III,IV	0.450	0.816	.034	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

R3HCC1–CCRCC (DFS)

Open the CCRCC breakdown →