R3HCC1

Across TCGA pan-cancer cohorts, R3HCC1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of R3HCC1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where R3HCC1 RNA is repressed in tumor relative to normal tissue. In most cancer types R3HCC1 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, KIRC, and KICH are the cancer types where R3HCC1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in R3HCC1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	IV	−0.469	<.001	9	view →
KIRC	Female	All	+0.406	<.001	7	view →
KICH	Female	All	−0.651	<.001	5	view →
LUAD	Female	All	−0.362	<.001	5	view →
UCEC	All	All	−0.437	.006	4	view →
BRCA	Female	All	−0.384	<.001	4	view →
CHOL	Female	All	+1.686	<.001	3	view →
BLCA	All	IV	−0.724	.009	3	view →
READ	Female	All	−0.882	.007	2	view →
KIRP	All	II,III,IV	+0.344	.021	2	view →
PRAD	All	All	−0.319	.004	2	view →
LUSC	All	All	−0.231	.005	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

R3HCC1–THCA

Open the THCA breakdown →