QTRT2

Across TCGA patient cohorts, QTRT2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,191 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible QTRT2-associated genes across cancer lineages are WDR43, SMC4, and ECT2. Each is linked with QTRT2 in more than 6 cancer types. Because this analysis shows association rather than direction, both QTRT2-to-partner and partner-to-QTRT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, QTRT2 versus WDR43 in LSCC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (QTRT2→partner) and Y-score (partner→QTRT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WDR43 →	+0.547	+0.230	<.001	<.001	3	7
BRCA	SMC4 →	+0.860	+0.312	<.001	<.001	3	6
LUAD	ECT2 →	+1.051	+0.231	<.001	<.001	3	6
LSCC	UMPS →	+0.675	+0.286	<.001	<.001	3	6
LUAD	CENPA →	+1.255	+0.246	<.001	<.001	3	6
LUAD	CENPF →	+1.252	+0.231	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,191 associations by consensus.

QTRT2 vs WDR43 — LSCC

Explore this scatter interactively →