QTRT1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, QTRT1 mutation is significantly associated with the RNA expression of many other genes, with 406 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible QTRT1-associated genes across cancer lineages are LINC01669, CYCSP53, and RPS28P8. Each is linked with QTRT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both QTRT1-to-partner and partner-to-QTRT1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (QTRT1→partner) and Y-score (partner→QTRT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCLINC01669 →+0.027+5.303<.001.00632
LGGCYCSP53 →+0.174+7.977<.001.00732
PRADRPS28P8 →+0.259+8.351<.001<.00132
SKCMMIR7845 →+0.368+3.449<.001.00932
HNSCPMM2P1 →+0.066+5.069<.001.00832
HNSCPRR13P7 →+0.113+5.124<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 406 associations by consensus.

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