QSOX2

Across TCGA patient cohorts, QSOX2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,792 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible QSOX2-associated proteins across cancer lineages are GTF3C4, WDR5, and RPL12_S38. Each is linked with QSOX2 in more than 8 cancer types. Because this analysis shows association rather than direction, both QSOX2-to-partner and partner-to-QSOX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, QSOX2 versus GTF3C4 in LSCC, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (QSOX2→partner) and Y-score (partner→QSOX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GTF3C4 →	+0.408	+0.665	<.001	<.001	3	9
GBM	WDR5 →	+0.334	+0.474	<.001	<.001	3	7
LSCC	RPL12_S38 →	+0.864	+0.543	<.001	<.001	3	7
LSCC	ATAD2 →	+0.551	+0.537	<.001	<.001	3	7
GBM	SMC2 →	+0.702	+0.481	<.001	<.001	3	7
GBM	SMC4 →	+0.616	+0.384	.001	.007	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,792 associations by consensus.

QSOX2 vs GTF3C4 — LSCC

Explore this scatter interactively →