QSOX1

Across TCGA cell cohorts, QSOX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,427 significant associations in total. BONE shows the largest number of these associations.

The most reproducible QSOX1-associated GO terms across cancer lineages are Regulation of proteolysis, Negative regulation of protein maturation, and Integrin-mediated signaling pathway. Each is linked with QSOX1 in more than 16 cancer types. Because this analysis shows association rather than direction, both QSOX1-to-partner and partner-to-QSOX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of proteolysis grouped by QSOX1-low versus QSOX1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (QSOX1→partner) and Y-score (partner→QSOX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of proteolysis →	+0.104	+2.041	.003	.004	3	17
SOFT_TISSUE	Negative regulation of protein maturation →	+0.274	+2.066	<.001	<.001	3	16
BONE	Integrin-mediated signaling pathway →	+0.253	+2.745	<.001	<.001	3	16
BONE	Regulation of plasminogen activation →	+0.356	+3.458	<.001	<.001	3	15
BONE	Regulation of protein maturation →	+0.270	+3.156	<.001	<.001	3	15
BONE	Regulation of protein processing →	+0.242	+3.066	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,427 associations by consensus.

Regulation of proteolysis by QSOX1 expression — STOMACH

Explore this box plot interactively →