Across TCGA patient cohorts, QRFP mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible QRFP-associated genes across cancer lineages are MTND4P33, RN7SL498P, and RNA5SP455. Each is linked with QRFP in more than 1 cancer types. Because this analysis shows association rather than direction, both QRFP-to-partner and partner-to-QRFP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (QRFP→partner) and Y-score (partner→QRFP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MTND4P33 →	+0.058	+6.993	<.001	<.001	3	1
SKCM	RN7SL498P →	+0.151	+5.097	<.001	.008	3	1
UCEC	RNA5SP455 →	+0.361	+5.470	<.001	.001	3	1
UCEC	TRAJ52 →	+0.995	+3.434	<.001	.006	3	1
UCEC	TRAJ46 →	+0.474	+4.453	<.001	.006	3	1
UCEC	TRAJ42 →	+1.332	+4.776	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

QRFP survival (RNA) · tumor vs normal (RNA) · all QRFP data types