Across TCGA cell cohorts, QRFP mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible QRFP-associated genes across cancer lineages are IFNA8, ADGRE3, and KRT6C. Each is linked with QRFP in more than 1 cancer types. Because this analysis shows association rather than direction, both QRFP-to-partner and partner-to-QRFP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (QRFP→partner) and Y-score (partner→QRFP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	IFNA8 →	+0.038	+4.930	<.001	.008	3	1
SOFT_TISSUE	ADGRE3 →	+0.006	+5.977	<.001	.001	3	1
SOFT_TISSUE	KRT6C →	+0.013	+4.930	<.001	.008	3	1
SOFT_TISSUE	PGK2 →	+0.209	+4.930	<.001	.008	3	1
SOFT_TISSUE	GSTA5 →	+0.025	+4.930	<.001	.008	3	1
SOFT_TISSUE	SLC22A24 →	+0.006	+5.977	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

QRFP survival (RNA) · tumor vs normal (RNA) · all QRFP data types