Across TCGA cell cohorts, QRFP mutation is significantly associated with the mutation status of many other genes, with 265 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible QRFP-associated genes across cancer lineages are PIK3CD, BICDL2, and SOGA1. Each is linked with QRFP in more than 1 cancer types. Because this analysis shows association rather than direction, both QRFP-to-partner and partner-to-QRFP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (QRFP→partner) and Y-score (partner→QRFP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	PIK3CD →	+5.066	+4.502	.007	.007	1	2
UPPER_AERODIGESTIVE_TRACT	BICDL2 →	+5.392	+5.392	.004	.004	1	2
SOFT_TISSUE	SOGA1 →	+5.066	+4.502	.007	.007	1	2
SOFT_TISSUE	MARF1 →	+5.066	+4.502	.007	.007	1	2
SOFT_TISSUE	LRRC66 →	+5.066	+4.502	.007	.007	1	1
SOFT_TISSUE	ZNF292 →	+5.651	+5.651	<.001	<.001	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 265 associations by consensus.

Exploration

QRFP survival (RNA) · tumor vs normal (RNA) · all QRFP data types