QPCTL

Across TCGA pan-cancer cohorts, QPCTL mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated QPCTL data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher QPCTL mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated QPCTL expression acts as an unfavorable survival marker, although some lineages such as HNSC and LSCC show a favorable association.

CCRCC, HNSC, and LSCC are the cancer types where QPCTL mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	II,III,IV	0.125	0.904	.024	7	view →
HNSC	OS	Median	III,IV	1.000	0.449	.023	6	view →
LSCC	DFS	Tertile	II,III,IV	1.000	0.506	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

QPCTL–CCRCC (DFS)

Open the CCRCC breakdown →