QPCTL

Across TCGA cell cohorts, QPCTL RNA expression is significantly associated with the go_rna of many other GO terms, with 4,063 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible QPCTL-associated GO terms across cancer lineages are IMP biosynthetic process, Intestinal stem cell homeostasis, and Carbohydrate derivative catabolic process. Each is linked with QPCTL in more than 8 cancer types. Because this analysis shows association rather than direction, both QPCTL-to-partner and partner-to-QPCTL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IMP biosynthetic process grouped by QPCTL-low versus QPCTL-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (QPCTL→partner) and Y-score (partner→QPCTL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	IMP biosynthetic process →	+0.154	+0.964	<.001	<.001	3	9
SOFT_TISSUE	Intestinal stem cell homeostasis →	+0.191	+0.852	<.001	<.001	3	9
SKIN	Carbohydrate derivative catabolic process →	+0.040	+0.627	<.001	<.001	3	9
CNS	Putrescine biosynthetic process from arginine, via ornithine →	-0.107	-0.733	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Protein localization to microtubule plus-end →	+0.227	+0.810	.008	.006	2	9
LUNG_NSCLC_LUSC	Protein localization to microtubule end →	+0.227	+0.810	.008	.006	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,063 associations by consensus.

IMP biosynthetic process by QPCTL expression — URINARY_TRACT

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