QKI

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, QKI RNA expression is significantly associated with the protein abundance of many other proteins, with 15,144 significant associations in total. COAD shows the largest number of these associations.

The most reproducible QKI-associated proteins across cancer lineages are HOOK1, TLN1, and PLS3. Each is linked with QKI in more than 6 cancer types. Because this analysis shows association rather than direction, both QKI-to-partner and partner-to-QKI results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, QKI versus HOOK1 in LSCC, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (QKI→partner) and Y-score (partner→QKI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCHOOK1 →-0.382-0.328.001.00137
COADTLN1 →+0.353+0.568<.001<.00136
OVPLS3 →+0.857+0.750<.001<.00136
BRCADAB2 →+0.369+0.556<.001<.00136
COADFMNL3 →+0.462+0.823<.001<.00136
OVC1QC →+0.616+0.697<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,144 associations by consensus.

QKI vs HOOK1 — LSCC

Per-sample scatter of QKI vs HOOK1 in LSCC (Pearson r = -0.35).

Explore this scatter interactively →

Exploration